Pharmacy Program Updates: Prior Authorization Changes Effective March 1, 2025

Dec. 26, 2024

The pharmacy prior authorization program encourages safe, cost‑effective medication use by allowing coverage when certain conditions are met. A clinical team of physicians and pharmacists develops and approves the clinical programs and criteria for medications that are appropriate for PA by reviewing FDA-approved labeling, scientific literature, and nationally recognized guidelines.

See below for upcoming changes to the standard pharmacy PA programs. These changes affect members with prescription drug benefits administered by Prime Therapeutics.

Effective Date

PA Program Description of Change Drug Lists PA or Specialty PA
March 1, 2025 ATTR Amyloidosis PAQL New criteria requirements Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 Health Insurance Marketplace, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select Specialty PA
March 1, 2025 IL-5 Inhibitors PAQL New criteria requirements Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select Specialty PA
March 1, 2025 Ohtuvayre PAQL New program Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select

Specialty PA

March 1, 2025

Primary Biliary Cholangitis PAQL

New criteria requirements Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select Specialty PA
March 1, 2025 Xolair PA New criteria requirements Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select Specialty PA
April 1, 2025 HCPA Biologic Immunomodulators PAQL

New criteria requirements

Basic, Basic Annual, Enhanced and Enhanced Annual Specialty PA
April 1, 2025 Sohonos PAQL New program Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select Specialty PA
April 1, 2025 Therapeutic Alternatives PAQL New program targets Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select PA
April 1, 2025 VMAT2 Inhibitors PAQL New criteria requirements Basic, Basic Annual, Enhanced, Enhanced Annual, 2024 HIM, 2025 HIM, Balanced, Performance, Performance Annual and Performance Select Specialty PA

 

Refer to our Prior Authorization and Step Therapy Programs page for a list of programs and target drugs, the PA request form and related information.

Treatment decisions are always between you and your patients. Coverage is subject to the terms and limits of your patients’ benefit plans. Please advise them to review their benefit materials for details.

If your patients have any questions about their pharmacy benefits, they can contact the number on their member ID card. They can also visit our member site and log in to Blue Access for MembersSM or MyPrime.comfor helpful tools and resources.

Prime Therapeutics LLC is a separate company contracted by Blue Cross and Blue Shield of Illinois to provide pharmacy solutions. BCBSIL, as well as several independent Blue Cross and Blue Shield Plans, has an ownership interest in Prime Therapeutics. MyPrime.com is a pharmacy benefit website offered by Prime Therapeutics LLC.

The information mentioned here is for informational purposes only and is not a substitute for the independent medical judgment of a physician. Physicians are to exercise their own medical judgment. Pharmacy benefits and limits are subject to the terms set forth in the member’s certificate of coverage which may vary from the limits set forth above. The listing of any particular drug or classification of drugs is not a guarantee of benefits. Members should refer to their certificate of coverage for more details, including benefits, limitations and exclusions. Regardless of benefits, the final decision about any medication is between the member and their health care provider.

Checking eligibility and benefits and/or obtaining prior authorization is not a guarantee of payment of benefits. Payment of benefits is subject to several factors, including, but not limited to, eligibility at the time of service, payment of premiums/contributions, amounts allowable for services, supporting medical documentation, and other terms, conditions, limitations, and exclusions set forth in the member’s policy certificate and/or benefits booklet and or summary plan description. Regardless of any prior authorization or benefit determination, the final decision regarding any treatment or service is between the patient and the health care provider. If you have any questions, call the number on the member's ID card for BCBSIL.